Abstract:Based on the panel data of large and medium-sized industrial enterprises and 16 cities in Anhui Province in 2001~2016, we used the DEA-Malmquist productivity index to calculate the TFP and its decomposition, and further analyzes the factors that affect the total factor productivity and the technical progress index through the empirical method. The results showed that: (1) During the study period, the Malmquist index and technical progress index of large and medium industrial enterprises in Anhui province were more than 1 in most years. The improvement of TFP was mainly due to the improvement of technical progress. (2) Foreign direct investment and corporate profitability have a positive impact on total factor productivity and technical progress rate; The scale of enterprises and government funds have negative impact on total factor productivity and technical progress rate; Industry concentration is not significant to total factor productivity, but has a negative impact on the rate of technical progress. Finally, on the basis of the results of this study, some suggestions are put forward to improve the total factor productivity of industrial enterprises in Anhui province.