Interdisciplinary research has become an important method and path of collaborative innovation, engineering ethics has become the model of interdisciplinary collaboration research, and the establishment of United States’ social environmental research center comprehensively promotes multidisciplinary collaborative innovation from system and specification. Honors seminar also serves as an important model of collaborative research in teaching of American higher education. Therefore, the research and reference to USA engineering ethics, social environmental research center, honors seminar operational experience and management specification, which will help promote interdisciplinary cooperation in scientific research、education and other aspects between all of kinds of school, and also help promote the development of collaborative innovation.