Abstract:this article is based on the Chinese industry from 2004 to 2011 in 33 subdivision industry panel data, using threshold regression techniques, the empirical study on the impact of trade liberalization on r d technology progress heterogeneous threshold effect. Research shows that: (1) trade liberalization and development of technological progress is “N” model of the nonlinear relationship, namely with trade liberalization level from low to high, the research and development technology produces lower after improve to reduce the influence of the first law; (2) research and development technology progress effect of trade liberalization also depends on the level of marketization, foreign direct investment effect, such as in environmental regulation, foreign direct investment and industry profits threshold conditions, trade liberalization impact on r d technology progress are negatively to the overall effect, and under the condition of marketization level threshold is inverted “U” type characteristic, under the condition of enterprise scale threshold is “U” type feature. (3) under the condition of different threshold, trade liberalization on the threshold of the r d technology progress effect obvious heterogeneity characteristic industry, which has a negative impact of industry distribution is concentrated.