Abstract:Under the market environment, associations of science and technology will become more dependent on social choice. Currently, associations of science and technology in Wuhan have a higher self -survival degree. The survival space are narrow, lack of vitality, and present the "Matthew effect" gradually; And lack of professionals, shortage of funds, unbalance development, high degree of resource dependence, affected highly by the elite class , low anti-risk ability are the important reasons for the associations of science and technology weakening in survival ability; Presently, it is necessary to further promote the marketization operation of associations of science and technology in Wuhan ,build the competition mode of one industry to many associations (one to many), set up the full-time personnel system, adjust the structure of the staff, build the performance evaluation system,change the relationship between the government and the associations of science and technology, expand the capital source channel , improve the supervision system, improve market viability of associations of science and technology.