Abstract:The research achievements of social network theory and enterprise management innovation theory are combied,the listed companies in high and new technology industry of China are as samples, to explore the relationship between the entrepreneur network and enterprise management innovation ability. Research shows that entrepreneurs transverse relationship network has positive effect on management innovation ability, entrepreneur agency relationship network has negative effect on management innovation ability; While entrepreneurs longitudinal network has negative correlation with marketing efficiency, and is related to operation efficiency and management efficiency. Therefore, entrepreneurs must attach importance to building enterprise relationship network with suppliers and customers, and carefully build agency relationship network, and create the appropriate relationship network with government departments.