Abstract:Sophia Antipolis is the most important strategic science park in European, having become Europe’s “Telecom valley”. Based on the thoughts of “social technologies”, researching on the roles of “social technologies” in the transition of Sophia Antipolis from three levels, industry models, policies and regulations, and social spirit. The development and innovations of “social technology” represented by “branding of science and technology park” and “Local production network” the level of industry models, the “medium and small-sized enterprises policies” and “motion of industry cluster development” on the level of policies and regulations, the “decentralization movement” on the level of social spirit. The development of “social technology” in the transition of Sophia Antipolis giving us important enlightenment.