Abstract:Collaborative innovation plays an important role in promoting the economic de-velopment of the “new normal”.An evolutionary game model of “goverment-industry-university-institute”cooperative innovation is established in this paper.The collaborative innovationof cooperaive stability mechanism is analysised.The paper obtains some conclusions,such as industry and university-institutes’ choice depends on the comparision of parameter values.Adding the government who is the body of economic interests to the game model willreduce the robustness of collaborative innovation cooperation.According to these conclusio-ns,the paper puts forward some policy recommendations which can promote the “goverment-industry-university-institute”cooperativeinnovation effectively.