Abstract:The realization of America’s reindustrialization highlights the core innovation advantages of top manufacturing, establishing upgrading of industrial structure on the basis of Innovation. The core focus of enhancing America’s innovative economy driving force is to promote and develop the configuration structure input and innovation of the advanced factor of production oriented by market such as technological resources, capital resources, human talent resources, mechanism resources that innovation of top manufacturing needs. The advantage of creation and restructuring of configuration structure of the advanced factor of production assists America of taking over and maintaining the leading position of technology, research and developing and manufacturing, driving a new round of economic growth cycle. However, the transformation course from our countrie’s “high-growth, low-innovation” manufacturing to “ innovation-drived growth” remains long way to go, which means we should focus on the input advanced factor of production and other innovation resources, regulating the inner industrial structure of manufacturing. We should be well prepared for the coming large scale of high technology innovation, aim at promoting the developing level of our countrie’s technical innovation resources system of manufacturing.