Abstract:Along with the rapid development of life sciences, scholars have shown great interest in the cross-over study with it while gene theory play a pivotal role and the relevant research have made remarkable achievements. Based on the common characteristics between building sciences and life sciences, scholars have turned their focus on the cross-over study in building science and life science which is originated in the widely used of the bionics and life cycle theory. Gene theory, an innovative methodology and analysis tools from micro to macro, have been introduced into building sciences over the years. In this paper, we comprehensively analyzed the achievement in cross-over study between building sciences and life sciences and divided the existing research into three dimensions. In view of present achievement and some potential problems, some suggestions are put forward to further promote the theoretical integration.