Abstract:Based on the resource dependence theory, statistical survey research method is employed in the thesis mainly by questionnaire of 53 professional universities firstly. Secondly, regression model empirical research is used. The results show that the relationships between the mode of commissioned research, the mode of building a cooperative platform, the mode of training talents together, the mode of school-enterprise strategic alliance and the university scientific research performance are partly mediated by researchers structures and research funding; the relationship between the mode of technology transformation and the university scientific research performance is fully mediated by research funding. Thus, professional universities should carry out various forms of cooperation projects, strengthen investment in research personnel and research funding, make full use of personnel, funds, and platform which provided by cooperation project, in order to improving scientific research performance.