Abstract:National High-tech Zone in Shaanxi province nowadays faces an during its innovation development, a paradox between a strong investment in science and technology resources and a lagging economic development. Based on the review of related literatures, this paper constructed a comprehensive evaluation index system of innovation development level, involving four aspects and 16 indicators, i.e. the innovation investment ability, the innovation organizational ability, the innovation output capacity, the environmental supporting capacity. Using the Entropy-weighted Topsis Index method, this paper made a comprehensive evaluation of innovation development for seven national high-tech zone in Shaanxi province. The result showed that the innovation investment ability, the innovation organizational ability, the innovation output capacity will play a decisive role in the innovation development of Shaanxi national high-tech Zone, while the relative value distribution of environment supporting capacity is more balanced, which is not a determinant for its innovation development.