Abstract:With the perspective of the theory of Public Domain of intellectual property law, this article discusses the characteristics, equity and benefits principle of traditional medical knowledge. Combined with analysis of the protective measures and effect of traditional medical knowledge constructed in some countries, Reviewing the protection framework and defects of Traditional Chinese Medical (TCM)knowledge and related resources in China, the article puts forward that the nation needs to take measures to strive for the legal status and rights of TCM and related knowledge in the international intellectual property system, in order to facilitate the connection between TCM and modern science and international knowledge system, and to promote the development of traditional Chinese medicine under the background of economic and cultural globalization.