Abstract:On the basis of enterprise innovation network evolution model, we proposed the concept of innovation capacity nodes ,and constructed cascade innovation network failure reliability model, then simulated the cascading failure reliability of the volatility, homeostasis and atrophy network. Simulation data show that: under conditions of random attack node, the failure rate of volatility network is higher than the other two networks. And then we deliberately attacked the network note which is according to the degree centrality in descending order , the node failure rate of the homeastasis network is higher than the network instability network when node with the higher degree centrality is attacking. But when the degree centrality is smaller, the node failure rate of dynamic balance network is gradually lower than the unrest network, and the node failure rate of shrinking network is at its lowest. In addition, if the attack flow betweenness centrality node, the innovation network loss rate of volatility network is highest between the three networks. Experimental results show that the integrated innovation capability network of volatility network is maximum , but the reliability is low.