Abstract:The 2012-2015 SME Board of 221 enterprises as the research sample. The study shows that between ownership structure and R&D investment has significant correlation, and with the enterprise ownership concentration degree rise, the enterprise R&D investment intensity has increased first and then decreased and then increased, the specific relationship between the two is "N" glyph cubic curve. Equity balance degree and R&D investment is positive linear relationship. Management layer and the average age of R&D investment has a significant negative correlation,educational level and R&D investment intensity has a significant positive correlation. And management layer average age and education level of ownership structure and R&D inputs have a positive moderating effect.