Abstract:The chasm between manufacturers cost and user cost is difficult to cross. However, with the rise of cloud manufacturing and other new manufacturing model, to cooperation across the organization cost for system coordination and optimization become the key problem between manufacturer and user cooperation relationship . They are key facts formed the chasm between manufacturers cost and user cost that business model inflexibility of products manufacturing as the core connection, competition-oriented enterprise boundaries, the limitations of property rights gap under market mechanism, self-interested selection of decision-making agent by researched. Proposed to constructing value ecosystems, Product Service System, cooperation mechanisms of dynamic contract, cost synergies platform based on "Connection bonus" and cross-border as the path of crossing the chasm between manufacturers cost and user cost based on cloud manufacturing .This paper provides a cost synergies model as a valuable theoretical framework for across the organization based on cloud manufacturing. The theoretical framework is verified by case analysis.