Abstract:Developed provinces and cities play a leading role in implementing innovation-driven strategy and independent innovation strategy in China. Therefore, it is necessary for them to strengthen basic research. The basic research level evaluation index system was established, which includes basic research input, basic research output and basic research activities. Guangdong Province was taken as an example. Based on the statistical data from 2009 to 2014, the weight of each index was determined by entropy method, then, the basic research level of Guangdong province was evaluated. The results are as follows. First, the level of basic research of Guangdong Province is in constant progress, but has not reached a high level during the past 6 years. Second, the development of basic research in Guangdong Province is fluctuating, and there is a trend of decline in some aspects (indexes).Therefore, it is necessary to speed up the development of basic research in Guangdong by changing the concepts, improving the R D structure, cultivating basic research actors.