Abstract:China should strengthen structural reform of the supply front to increase the quality and efficiency of supply system and provide a growth impetus for sustainable economic development through system innovation and technological innovation. It is very urgent to establish technical resources sharing mechanism and promote the collaborative innovation. Through the questionnaire survey and in-depth interviews, we found that the influence factors of S&T resources sharing mainly exist in the market, the government policy, system, consciousness and environment, etc. The study built a system model of S&T resources sharing according to system dynamics theory, tries to demonstrate change rules and operational mechanism between elements. The main bodies of S&T resources include enterprise, universities, scientific research institutes and government department. Economic interests, performance objectives and value orientations constitute the internal driving forces of S&T resources sharing mechanism. The operational process of S&T resource sharing incorporate four core links, “open”, “access”, “innovation” and “sharing”, they are organic connection and move in circles. Finally, the study proposed to establish the platform of S&T resources sharing and innovation, perfect incentive mechanism of supporting S&T resources sharing, actively create social culture atmosphere of resource sharing. The study provide certain reference significance of exploring modes of S&T resources sharing and promoting collaborative innovation. It will help optimize the environment of S&T innovation and improve relevant policies for the government, and enhance the innovative performance and promote transformation and upgrading for the enterprises.