Abstract:In the economic transformation period, the agglomeration development of modern service industry has become the effective way of regional industrial development and new sources of regional economic growth. Based on the discussion of modern service industry agglomeration index and modified algorithm, the paper gives empirical research about the industrial agglomeration degree, industrial specialization level, industrial agglomeration structure and spatial distribution characteristics of modern service industry in Pearl River Delta region. Finally, the paper puts forward some policy suggestions from the aspects of guiding the differential agglomeration development of modern service industry, constructing the synergic development industrial ecosystem of modern service industry with manufacturing industry and optimizing the regional symbiotic development environment of modern service industry.