Abstract:on the basis of literature review, this paper compared and analyzed the representative characteristic zones of biological industry at home and abroad, systematically untangled and summarized the development status of biological industry in Guangzhou in the following aspects, the industrial scale, industrial cluster, industrial development environment, industrial technical support, etc.; analyzed the challenges and problems that the development of Guangzhou biological industry faces, namely, the competitive situation of domestic biological industry is very intense, Guangzhou City is lack of overall planning and layout for biological industry, the constructions of incubators and public service platforms are lagging, the combination of finance and technology is not close enough; put forward the following countermeasures to promote the development of biological industry, namely, improving the investment work, introducing R D institutions, cultivating headquarter economy of biological industry, promoting the constructions of incubators, constructing public service platforms, exploring the road of combining technology with finance, setting up collaborative innovation mode, expanding policy cooperation with Central Europe regions and strengthening the supports for innovative and entrepreneurial talents.