Abstract:University knowledge production was influenced by academic logic and market logic. The market logic required university knowledge production to be academic-oriented, while the market logic required university knowledge production to be market-oriented. With the transformation of institutional environment, the change of the contract relationship of knowledge production and the change of the concept of academic of university also made the academic logic of university knowledge production altered. Nowadays, the academic logic had crossing point as well as contradictions with market logic, and they achieved the logic balance in the change of university knowledge production. So as to response to both academic and market logic, academic firm will be the new type based on traditional types of university; constructing the continues institution and founding an innovational system of “Quadruple Helix” included by university, government, industry and civil society will be the direction of university knowledge production.