Abstract::The externality of industrial agglomeration promotes regional technological innovation, but its impact on regional environment and energy is often ignored. In this paper, through the construction of comprehensive consideration of environmental and energy technology innovation, green innovation index system, from the perspective of external space, to explore the influence of industry agglomeration level of green innovation, and using the panel threshold model empirical study. The study found that industrial agglomeration has a "U" double threshold effect of green innovation, agglomeration level is low, green innovation area inhibited industrial agglomeration; with the increase of the level of agglomeration, industrial agglomeration negative effect on green innovation gradually decreased; when the concentration level across the higher threshold value, industrial agglomeration has incentive effect on green innovation. Therefore, it is necessary to deal with the relationship between industrial agglomeration and green innovation.