Abstract:This paper establishes a set of index system of synergetic degree of knowledge-intensive business service and advanced manufacturing industry based on synergetics. The authors use coordination degree model of compound system, which was built based on grey relational theory and CRITIC method, to study the level of synergetic development of two industrial systems in Shanghai during the period from 2006 to 2015. The research shows that both the knowledge-intensive business service and advanced manufacturing industry in Shanghai have steadily developed in their own systems, especially, the order degree of knowledge intensive service industry has been improved significantly in recent years; However, after the early rapid development, the compound system is limited by the bottleneck of the development of advanced manufacturing industry and the lack of depth integration in various aspects, which leads the compound system can not coupl in structure and function. Finally, the process of synergetic development of compound system becomes slow.