Abstract:The paper analyzes the research literatures of Guangdong specialized towns from the time series and classification, and explores the difficulties in the development of specialized towns under the new normal condition. It points out that emancipating the mind, seeking truth from facts, seeking more creative ideas market; implementing the strategy of state-owned enterprises withdraw and private-owned enterprises enter for a good environment, facing development challenges for creating a win-win development pattern are the solutions for specialized town to achieve innovation and development.