Abstract:Science research laboratories have great resources advantage on operating science popularization activities. It is the important place of scientific education. However, the mechanism of carrying out the science popularization activities is not perfect in many research labs. In this paper, the case of key laboratory of tropical diseases control (Sun Yat-Sen University), Ministry of Education is taken as example to analyze the science popularization mechanism. Through strengthening the scientific management system, standardizing and specializing the science resources, making popular science activities brands, the lab has spread the scientific research achievements, which also improved the scientific quality of the public and enhanced the actual effect of the tropical diseases prevention and control. The experience might give a reference to other research laboratories to improve the science popularization form, mechanism and management, which help building the bridge between public and researchers.