Abstract:The purpose of this paper is to investigate how economic growth responses to financial development and technological innovation by SYS-GMM method based on the statistics of China’s thirty provinces and cities from 1998 to 2014. The results indicate that economic growth reacts positively and significantly :(1) to financial development from national or regional perspective;(2) to technological innovation only from national perspective;(3) to financial development and technological innovation from national and regional perspective after considering interaction between financial development and technological innovation. Additional analysis indicates that financial development negatively and significantly affects economic growth through technological innovation channel.