Abstract:With the scale of industrial clusters increasing,many problems are emerging,such as the serious homogeneity competition in industry clusters,lacking of effective communication and information sharing between enterprises,the ability of supply chain collaboration become weak and so on. At the same time,the development of electronic commerce not only has greatly changed the mode of production and organization in industrial clusters,but also promoted the further transformation and upgrading of industrial clusters to a great extent. Electronic commerce provides a rare opportunity for continuous innovation development of supply chain in industrial cluster.This paper reviews research status of the ability of supply chain coordination in industrial cluster, analyses the critical influence factors and external demand conditions of industrial cluster supply chain.Based on this,this paper attempts to confirming the driving effect of electronic commerce on industrial clusters and proposing corresponding proposition hypothesis. The propositions of this paper are tested by the case study,findings show that electronic commerce can contribute to information coordination of supply chain in industrial cluster, enhancing trust and cooperation among enterprises, integrating of market resources rapidly,facilitating collaboration and competition among enterprises of supply chain in industrial cluster.