Abstract:paper based on the current domestic and foreign representative Science Technology Innovation Center case, through the research on developing process, management experience and development gains and losses. It is concluded that the establishment of a world-class technology innovation center needs to break through the geographical boundaries, Through collaborative innovation ecosystem to promote various types of innovative elements. It is characterized by the development of science and technology, industry and economy. Will continue to upgrade the investment environment and industrial facilities as a prerequisite to the implementation of the strategic innovation center, and ensure the development of people-oriented policy guarantee mechanism