Abstract:In today's world, the development of think tanks is related to national policy formulation and international influence, and the think tanks have become an important component of the national soft power and an important force to promote social and economic development. However, the development of China's think tanks is not high quality and lack of innovation and other issues, the new normal economic development in Guangdong, the urgent need to accelerate the construction of scientific and technological innovation think tank, give full play to its role as a think-tank. Firstly, it analyzes the importance and necessity of the development of Guangdong's scientific and technological innovation think tank. Secondly, it analyzes the present situation and existing problems of the development of Guangdong's scientific and technological innovation think tank in detail. It points out that the number of think tanks in Guangdong's scientific and technological innovation think tank is increasing, But also in the institutional system, policy supply, social participation and so there are some limitations, its quality and level of domestic and foreign advanced science and technology think tank there are gaps and other issues; Then, from the construction of Guangdong innovative think tank development mechanism should pay attention to the basic attributes and the specific construction of the development mechanism of the two aspects pointed out that the specific direction of development; finally, it pointed out that through the system improvement, the system innovation, social participation and other aspects of the path to promote the development of science and technology innovation think-tank.