Abstract:Israel is one of the most prosperous countries in the development of new and high technology in the world. It enjoys the reputation of "the country of innovation", "second Silicon Valley" and "Middle East Silicon Valley". This paper mainly analyses of Israel science and technology innovation policy system, and learns from the advanced experience of Israel, and puts forward the countermeasures and suggestions for improving the policy system of innovation driven development in Guangdong, including the establishment of Guangdong decision advisory system, improving the incubation and cultivation policy of Guangdong, vigorously developing overseas investment risk, establishing a civil military integration and innovation development mechanism and cultivating a number of complex scientific and technological achievements to transform talent team.