Abstract:With the success of high-tech enterprises, the rise of some countries and the development of innovation theory, innovative ecosystems has become a new paradigm to adapt to today"s environment, which is consistent with the philosophy of the innovation and development strategy of China, and promoting the comprehensive innovation with scientific and technological innovation as the core. And the Creative Research Group is the most representative scientific and technological innovation team in the forefront of basic research in China. Its organizational mechanism and dynamic evolution connotation is consistent with the innovation ecosystem. From the perspective of innovation ecosystem, the cooperative network and timing evolution of excellent innovation group are studied, and exploring its process and law through the case study, has the significance of rich theoretical research and providing practical reference. Keywords: Creative research group; innovation ecosystem; cooperative network; temporal evolution; knowledge map