Abstract:In the first 17 years of the 21st century, the number of Japanese who won the Natural Science Nobel Prize reached as many as 17 people, ranking second in the world with the emergence of the Nobel Prize blowout phenomenon. These prizes are mainly the fruits of the sciences and technologies from 1970s to 1990s. It is the results of Japan"s long and steady investment for scientific research. By analyzing the scale and intensity, the source structure, the utilization structure and the activity types of R D investment about three decades since 1970s, it is found that the scale and intensity of Japanese R D investment are the basis for stimulating scientific and technological innovation, and it is also the material basis for wining Nobel Prize. Enterprise is the main source and utilization institutions of R D investment, forming a unique “Government-Industry-University-Academy system”. Activity types structure is stable and reasonable and the basic research attaches much attention. Based on the above research, the paper proposes some suggestions to China’s R D investment: Firstly, China should formulate appropriate scientific and technological development policies; Secondly, R D investment should be compatible with the stage of industrialization; Thirdly, China should also form a good government-industrial relations; Last but not least, China should coordinate the proportion of the basic research, applied research and development research, and continue to increase the investment of basic research.