Abstract:The agglomeration of science and technology services can reduce the management costs of service objects (enterprises), promote specialized investment and service development, and produce economies of scale and spillover effects. Through the investigation of Sichuan 2012-2016 science and technology service industry development data, select Guangdong, Jiangsu, Shandong, Zhejiang and Henan for 2012-2015 comparative study found: Sichuan science and technology services industry scale, industrial base, market scale and economic development out of sync; based on the data of the Sichuan science and technology service industry in 2016, analysis found that the lack of coordination in the format the structure, regional distribution, capital structure and industry support. In view of the synergy bias in the early stage of agglomeration of Sichuan science and technology service industry, constructs a "four - in - one" development model of "policy - regional - Industry - resources" from the perspective of synergy, in order to provide reference for related research and decision making.