Abstract:Large amount of research and empirical work have been done on the influencing factors of R&D investment by domestic and international scholars. However, most of the existing works focus on qualitative research of one or several aspects and the interactive effects that affect the R&D investment of enterprises, which mainly came up with qualitative conclusion. A small number of scholars applied quantitative analysis to express the mathematical relationship between one or several variables and R&D investment, but in terms of the large number of influencing factors, this quantitative analysis method has its own limitation. In order to explore a method of quantitative analysis of a large number of factors at the same time, this paper tries to analyze the manufacturing enterprises in stock markets of Shanghai and Shenzhen by using the analysis method of big data. The analysis target is set as more than 3.5% R&D input intensity to get quantitative optimization rules.