Abstract:Taken listed companies from 2009 to 2015 as the research sample, this paper investigates the mediating effect of compensation incentives which can alleviate the largeshareholders’ negative impact on corporate innovation. Using logit model, tobit model and regression model, we find that largeshareholders have negative impact on corporate innovation. The results suggest that the CEO compensation incentive (individual salary and shareholding) plays a partial role of mediating effect and the mediating effect accounts for 28%. Meanwhile, the CEO compensation incentive is completelymediate in non-state-owned enterprises samples. In state-owned enterprises, CEO compensation is partial mediate, but CEO’s shareholdings don’t have mediating effect. Our findings shows that enhancing the level of compensation incentives is an important way to alleviate thelargeshareholders’ negative impact on corporate innovation. This paper provides empirical evidence and research ideas for the management of " One share dominates exclusively".