Abstract:Based on symbiotic theory, this paper analyzes the symbiotic elements of industry-university-research-finance cooperation from the three dimensions of symbiosis unit, symbiosis mode and symbiotic environment, and puts forward the research hypothesis that the symbiotic elements affect the enterprise innovation performance. An empirical study was conducted on 376 enterprises in a number of different fields such as bio-pharmaceuticals, chemicals, electronics and mechanical equipment. Then this paper uses structural equation model to verify the research hypothesis. Research indicates: Among the symbiotic elements of industry-university-research-finance cooperation, the symbiotic elements that have the greatest impact on the innovation performance of enterprises are the symbiosis pattern, followed by the symbiotic environment, and the weakest impact factor is the symbiotic element. Aaccording to the conclusions of the research, it proposes the improvement of enterprise innovation performance.