Abstract:Knowledge integration and thinking association is the key to the success of interdisciplinary scientific research. Knowledge association integration focuses on the integration of knowledge as well as the integration of thinking and the impact of innovation environment. this paper selected the typical interdisciplinary research team in the field of intelligent manufacturing as the research object. Based on the grounded theory as the leading tool for exploratory research, knowledge association integration is influenced by knowledge, knowledge integration, main body factors, thinking associated and cooperation factors, knowledge absorptive capacity. Knowledge factor is the dynamic foundation of knowledge association integration. The main factor plays the role of cognitive regulation. The cooperation factor is the important support condition of knowledge association integration. The main points of construction and management of interdisciplinary research organization are put forward to the main content and theoretical model of influencing factors.