Abstract:By means of the mapping knowledge software CiteSpace V, this paper, makes a statistical analysis based on the 2424 representative literatures of entrepreneurial research published during 2007—2016 in the Web of Science Data base through the co-citation analysis and co-word analysis. The result shows that the hotspots mainly focus on the fields,such as open innovation,innovative firms,developing countries,in-depth interviews, innovative activity and other issues. In terms of factor analysis and evolution trend, formed by seven stages from regional innovation system to business ownership, to service industry, to social entrepreneurship, to firm performance, to knowledge spillover theory and then to business model. Furthermore, the future research trend can be summarized to four areas covered knowledge spillover theory,firm performance,business model and social entrepreneurship.On the basis of this, suggestions and countermeasures are proposed to provide reference and paradigm for future innovation and entrepreneurship research and practice.