Abstract:Science of Science is an interdisciplinary subject which takes science as its research object and integrates basic theory and application research. By briefly reviewing the theory of domestic science of science in the related literature, this paper revealed the research trends of science of science by two aspects, meta-research and the theory research of science of science. On the whole, the research of theoretical science of science in China has entered a new normal development. However, the research topics are relatively concentrated. Prosperity of the domestic theoretical science of science research to further promote the healthy and rapid development of domestic science of science theory should be based on the theory, discipline construction, research team, academic position and innovation achievements to build a systematic and standardized system of collaborative development of science and technology to promote China"s science of science research the prosperous development under the new normal.