Abstract:the Guangdong—Hong Kong—Macau Greater Bay Area has risen to national strategies,the paper summarizes the current situation of the technological innovation development of the Guangdong-Hong Kong-Macau Creater Bay Area.analyzes the existing problems and shortcomings in the process of development,puts forward countermeasures and suggestions to construct the technological innovation community in the Guangdong -Hong Kong-Macau Creater Bay Area,accelerates the integrated development of Guangdong, -Hong Kong-Macao Great Bay Area,we will step up efforts to build the Guangdong—Hong Kong—Macau Greater Bay Area into the world''s most important high-end manufacturing, and international innovation center for science and technology and industry.