Abstract:Based on the hypothesis of bounded rationality, the evolutionary game model is used to explore the choice of cooperation strategy among the participating new R & D institutions. By analyzing the benefit payoff matrix of the two parties, we can get the dynamic equation and the Jacobian matrix, and obtain the partial equilibrium point of the model, so as to get the final strategy choice of the parties with time and verify the evolution of the game system strategy through numerical simulation. at the same time, it analyzes the influencing factors of cooperative strategy selection of new R & D institutions under cooperative innovation. On this basis, from the cooperation model, business needs and policy environment, putting forward the strategy recommendations in the new R & D institutions in the sustainable development.