Abstract:Based on the perspectives of scientific misconduct in different degrees, four typical cases of scientific misconduct in the United States, Japan and China were taken as the research objects. By analyzing their case background, treatment process and treatment results, it was found that in typical cases of scientific misconduct, scientific research institutions acted as the primary responsibility subjects.,and the government, scientific research institutions and academic community have a clear time of intervention, emphasizing the legalization of governance In the case of controversial research behaviors, academic journals act as the main body and take preventive measures combining peer review and academic misconduct system, and each subject strengthens the principle of linkage education.