Abstract:This paper applies Strategic Niche Management(SNM) theory to build open innovation model of multi-agent participation in new R&D institutions, and form the network of multi-innovative resources,which providing a new perspective for social management innovation. The paper starts from the perspective of relation between new R&D institutions and social innovative networks based on SNM process, and makes an in-depth analysis of 5 aspects,including the development and transformation of technological innovation, the practical cases and mechanism of open innovation, innovative participators and innovative models in different degrees.It emphasizes coordinating relationship between multi-agent participators,which creating a positive internal and external environment for innovation.It is shown by comparing open innovation models with different innovative participators that completely open innovation of multi-agent participation can realize profit maximization.