Abstract:As a new pattern of collaborative innovation among governments, enterprises, universities, and research institutes, innovative R&D institutes have played an important role in promoting the transformation and upgrading of traditional industries, accelerating the industrialization of technological achievements, and making scientific and technological progress. However, the construction and development of innovative R&D institutes still lack systematic and specific guidance. Therefore, from the perspective of close cooperation, this paper aims to explore the construction and development pattern of innovative R&D institutes co-established by institution and government by taking Huazhong University of Science and Technology-Wuxi Research Institute as an example. Such pattern as “technology-driven institute” closes the gap between universities’ technological achievements and industrialization and realizes the transformation from scientific research progress to industrial support, thus providing a reference for the construction and development of other innovative R&D institutes.