Abstract:Based on the key indicators comparison, this paper analyzed the performance of the national innovation chain of China and the United States. The research shows that the gap between China"s science and technology innovation input and output scale and the United States is shrinking, but there is still a big gap in terms of R D intensity, talent training, scientific research influence, core technology capabilities and industrial competitiveness. In the future, China should focus on strengthening the two-wheel drive of technological innovation and institutional reform, improving the investment in research and development of the whole society, especially the intensity of R D investment in enterprises, striving to improve the level of national higher education personnel training, and strengthening the strategic orientation of S T innovation to the needs of the country and the economy, Promoting the opening up in the global vision, accelerating the construction of an innovative country, and supporting China’s world technological power construction.