Abstract:In this paper, the effects of China's fiscal and taxation policies on R&D activities of high-tech enterprises in GEM are analyzed, the research shows that tax preferences have significant positive effects on the R&D of the enterprises, and can effectively stimulate the enterprises to increase R&D investments, the effects of government subsidies are not significant. Further research has found that, there is a great difference in the effects of tax preference on the technological innovation of enterprises in different regions, and the incentive effects of R&D in the east, middle and western regions are increased in sequence, government subsidies have a certain incentive effects on the R&D investments of high-tech enterprises in the western region, but it is difficult to promote the scientific and technological innovation of high-tech enterprises in the eastern and central regions. Based on this, the paper puts forward some suggestions to take into account the balance between tax preferences and government subsidies, rely on the support of tax preferences, and formulate different tax preferences and government subsidies policy according to the regional characteristics.