Abstract:This paper uses the innovation knowledge output and the innovation economic output to measure regional innovation performance separately, and establishes spatial measurement models to empirically examine the impact of innovation resource flows on regional innovation performance and the regulatory role of financial agglomeration, the results show: Innovative resource flows can promote regional innovation performance and generate positive spatial spillovers; Financial agglomeration positively regulates the relationship between innovation resource flows and innovative knowledge output in the same region, but has a negative effect on the relationship between innovation resource flows and innovative knowledge output in neighboring regions; When using innovative economic output to measure innovation performance, financial agglomeration does not significantly regulate the relationship between innovation resource flows and innovation performance in the same region, yet shows a significant negative adjustment effect on the relationship between innovation resource flows and innovation performance in neighboring regions.