Abstract:Realizing the transformation and upgrading of China"s manufacturing industry is a major requirement for socialism with Chinese characteristics to enter the new era of economic development. It is also one of the important issues that the community has closely watched and urgently needs to solve. Based on the global value chain theory, this paper believes that with the advancement of a new round of scientific and technological revolution and industrial transformation, technological innovation with intelligent manufacturing as the core will significantly expand the value space of production links and promote the flattening of the smile curve of traditional value chain distribution. Based on this, the article puts forward an effective path for the transformation and upgrading of manufacturing industry, including leading the division of labor in the global industrial chain, broadening the chain of intelligent manufacturing industry, and building an intelligent manufacturing ecosystem. Through the above effective countermeasures, the “low-end locking” dilemma of the value chain of China"s manufacturing industry in the global production network will be changed, and the transformation and upgrading of China"s manufacturing industry will be realized.