Abstract:As the theoretical system and content framework of the science of science & technology (S&T) policy have not been well formed and widely accepted, this paper analyzes the main contents of S&T policy studies and policy practices in and abroad China, investigates the evolution of S&T policy relevant concepts and connotations, and comprehensively summarizes the theories of science of S&T policy from three disciplines' perspectives (i.e., science of science, innovation economics and public policy). Under the framework of S&T governance system and the demand of the modernization of S&T governance in China, the paper proposes the three-level content framework of science of S&T policy, which includes S&T strategy (macro-level), innovation system and policy tools (meso-level) and policy process (micro-level), in order to provide support for the development of science of S&T policy.