Abstract:Exploring the management and operation system that conforms to the law of innovation is the basic support for the construction and development of national laboratories. Through field research and interviews, the author systematically combed the exploration and practical experience of various laboratories in China in the process of creating national laboratories, from the laboratory construction mode and administrative subordination, resource allocation mechanism, incentive mechanism, assessment and evaluation mechanism, In-depth analysis of the institutional mechanisms and causes of the results transformation and intellectual property protection, and further put forward the overall ideas and targeted recommendations based on existing problems and reasons, in order to optimize the integration of national laboratory construction and scientific and technological resources during the "14th Five-Year Plan" period. Provide basic reference and strong support.