Abstract:Compared with the world's three major Bay Areas, China's Beijing-Tianjin-Hebei urban agglomeration, the Yangtze River Delta urban agglomeration and the Guangdong, Hong Kong, Macao and Dawan Districts have formed a certain number of economic growth, innovative resource agglomeration, and scientific and technological achievements. Comparative Advantage, but in the quality of economic development, originality, the leading level of colleges and universities and enterprises, and the open innovation ecology. There are also some shortcomings in terms of aspects. In this regard, China should seize the strategic turmoil of the fourth scientific and technological revolution, promote the establishment of a central overall planning, local leading and promoting work mechanism, major projects, major bases to prioritize the layout of science and technology innovation centers, and further strengthen the basic research and application of basic research system deployment, Intensify efforts to cultivate a number of innovative entities with strong innovation capabilities, support science and technology innovation centers to vigorously promote the construction of international innovation and ecology, and study and formulate the evaluation index system of science and technology centers.